Memantine hydrochloride
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256 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 5 | 13 | 15 | 25 | 14 | 71 |
| Cognitive dysfunction | D060825 | — | G31.84 | 2 | 9 | 9 | 4 | 3 | 24 |
| Dementia | D003704 | EFO_0003862 | F03 | — | 4 | 4 | 7 | 9 | 24 |
| Healthy volunteers/patients | — | — | — | 10 | 1 | — | 2 | — | 13 |
| Autistic disorder | D001321 | EFO_0003758 | F84.0 | 1 | 6 | 2 | 1 | 2 | 12 |
| Schizophrenia | D012559 | EFO_0000692 | F20 | 1 | 4 | 5 | 2 | 1 | 11 |
| Autism spectrum disorder | D000067877 | — | F84.0 | 1 | 4 | 2 | 1 | 3 | 11 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | 1 | 1 | 5 | 3 | 10 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | 1 | 1 | 2 | 5 | 2 | 10 |
| Sclerosis | D012598 | — | — | — | 7 | 3 | 1 | — | 9 |
Show 49 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 2 | 2 | 4 | — | — | 7 |
| Obsessive-compulsive disorder | D009771 | EFO_0004242 | F42 | 1 | 3 | 2 | — | 1 | 6 |
| Compulsive personality disorder | D003193 | — | F60.5 | 1 | 3 | 2 | — | 1 | 6 |
| Amyotrophic lateral sclerosis | D000690 | EFO_0000253 | G12.21 | — | 5 | 2 | — | — | 5 |
| Motor neuron disease | D016472 | EFO_0003782 | G12.2 | — | 5 | 2 | — | — | 5 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | 1 | 1 | 2 | — | 2 | 5 |
| Neuralgia | D009437 | EFO_0009430 | — | — | 3 | 1 | — | — | 4 |
| Cognition disorders | D003072 | — | — | — | 1 | 3 | — | 1 | 4 |
| Carcinoma | D002277 | — | C80.0 | — | 2 | 3 | — | — | 4 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | — | 3 | 1 | — | — | 4 |
Show 43 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Developmental disabilities | D002658 | EFO_0003852 | F89 | — | 3 | — | — | 1 | 4 |
| Asperger syndrome | D020817 | EFO_0003757 | F84.5 | — | 3 | — | — | 1 | 4 |
| Glioblastoma | D005909 | EFO_0000515 | — | 2 | 2 | — | — | — | 3 |
| Tobacco use disorder | D014029 | — | F17 | 2 | 1 | — | — | — | 3 |
| Dyslexia | D004410 | EFO_0005424 | F81.0 | — | 3 | — | — | — | 3 |
| Fragile x syndrome | D005600 | — | Q99.2 | — | 1 | — | — | 2 | 3 |
| Systemic lupus erythematosus | D008180 | EFO_0002690 | M32 | — | 1 | — | — | 1 | 2 |
| Alcohol drinking | D000428 | EFO_0004329 | — | — | 2 | — | — | — | 2 |
| Diabetic neuropathies | D003929 | EFO_1000783 | — | — | 1 | — | — | — | 1 |
| Herpes zoster | D006562 | EFO_0006510 | B02 | — | 1 | — | — | — | 1 |
Show 23 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Central nervous system diseases | D002493 | — | G96.9 | 1 | — | — | — | 1 | 2 |
| Mental disorders | D001523 | EFO_0000677 | F91.9 | 1 | — | — | — | 1 | 2 |
| Gliosarcoma | D018316 | — | — | 1 | — | — | — | — | 1 |
| Crush injuries | D000071576 | — | T14.8 | 1 | — | — | — | — | 1 |
| Sleep deprivation | D012892 | — | F51.12 | 1 | — | — | — | — | 1 |
| Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
| Subdural hematoma | D006408 | — | — | 1 | — | — | — | — | 1 |
| Hematoma | D006406 | EFO_0010680 | — | 1 | — | — | — | — | 1 |
| Subdural hematoma chronic | D020200 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neurodegenerative diseases | D019636 | EFO_0005772 | G31.9 | — | — | — | — | 3 | 3 |
| Tauopathies | D024801 | — | — | — | — | — | — | 2 | 2 |
| Anemia | D000740 | EFO_0004272 | D64.9 | — | — | — | — | 1 | 1 |
| Hypoxia | D000860 | — | R09.02 | — | — | — | — | 1 | 1 |
| Hyperhomocysteinemia | D020138 | — | — | — | — | — | — | 1 | 1 |
| Vitamin b 12 deficiency | D014806 | EFO_0000734 | E53.8 | — | — | — | — | 1 | 1 |
| Tdp-43 proteinopathies | D057177 | — | — | — | — | — | — | 1 | 1 |
| Iron deficiencies | D000090463 | — | E61.1 | — | — | — | — | 1 | 1 |
| Spinal cord injuries | D013119 | EFO_1001919 | — | — | — | — | — | 1 | 1 |
| Deep brain stimulation | D046690 | — | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Safety
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Adverse Events
Top Adverse Reactions
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1,505 adverse events reported
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